Table 3.
Characterization of chimeric kidney donors
| Peripheral blood chimerism at time of kidney harvest |
||||
|---|---|---|---|---|
| Animal # | HSC recipient MHC | HSC donor MHC1 | Lymphoid (% donor) | Myeloid (% donor) |
| 20311 | AD | AC | ≥98 | ≥98 |
| 20680 | AD | AC | ≥98 | ≥98 |
| 20407 | CC | AA | 30 | 75 |
| 21557 | AD | AC | 85 | ≥98 |
MHC, major histocompatibility complex; pSCF, porcine stem cell factor; HSC, hematopoietic stem cells; HCT, hematopoietic cell transplantation; VCA, vascularized composite allograft; DLI, donor leukocyte infusion; BMT, bone marrow transplantation.
1
The source of HSC donor cells for all chimeric donors except for #20407 was pIL-3/pSCF-mobilized HSC. Animal #20407 received HSC cells from bone marrow.