Table 1. Alcohol consumption and socio-demographic characteristics by ALDH2 polymorphism rs671 in men and women from the Phase 3 of Guangzhou Biobank Cohort Study (2006–8).

	ALDH2 polymorphism rs671
	Two inactive alleles (AA)	One inactive allele (GA)	No inactive alleles (GG)	†P value
Men
Number of participants	220	971	1,130
Alcohol units, 10g ethanol per day, Geometric mean (95% CI)	0.55 (0.08–3.96)	1.28 (0.97–1.69)	2.49 (2.17–2.87)	<0.001
Gamma-glutamyltransferase, U/L, Geometric mean (95% CI)	25.0 (23.4–26.6)	26.1 (25.2–27)	30.2 (29.1–31.4)	<0.001
Age, years, Mean (SD)	63.3 (7.7)	63.8 (7.6)	63.4 (7.5)	0.40
Education, %
Primary or below	25.5	30.4	27.6	0.45
Middle School	58.6	55.7	56.8
College or above	15.9	13.9	15.6
Smoking status, %
Never	38.2	37.0	37.4	0.62
Former	29.6	25.5	26.8
Current	32.3	37.5	35.8
Physical activity, %
Inactive	8.2	7.9	7.8	0.32
Moderate	28.6	33.5	35.8
Active	63.2	58.6	56.4
Women
Number of participants	231	1,091	1,435
Alcohol units, 10g ethanol per day, Geometric mean (95% CI)	0.31 (0.004–25.43)	0.36 (0.24–0.54)	0.48 (0.36–0.63)	0.22
Gamma-glutamyltransferase, U/L, Geometric mean (95% CI)	20.2 (19.0–21.4)	21.5 (20.8–22.2)	20.4 (19.8–21.0)	0.25
Age, years, Mean (SD)	59.9 (7.0)	60 (7.3)	60.1 (7.3)	0.91
Education, %
Primary or below	42.4	41.7	40.4	0.62
Middle School	50.7	50.1	52.6
College or above	6.9	8.3	7.0
Smoking status, %
Never	98.7	97.2	97.8	0.37
Former	0.9	0.9	1.1
Current	0.4	1.9	1.2
Physical activity, %
Inactive	4.8	5.9	7.8	0.11
Moderate	27.7	24.5	22.7
Active	67.5	69.7	69.5

†P-value from analysis of variance (ANOVA) for continuous variables and from a χ² test for categorical variables, 2 sided; Alcohol unit and GGT were log-transformed before the ANOVA analysis.