Table 2. Number and class of antihypertensive medications according to the tertile of aortic pulse wave velocity.
Parameter | PWV tertile Low | PWV tertile Medium | PWV tertile High | Overall | P Value |
---|---|---|---|---|---|
N | 60 | 60 | 59 | 179 | |
Antihypertensive drugs (n) | 2.6 ± 1.3 | 2.7 ± 1.4 | 2.9 ± 1.2 | 2.7 ± 1.3 | 0.42 |
No antihypertensive drug n(%) | 2 (3.3%) | 3 (5%) | 1 (1.7%) | 6 (3.4%) | 0.61 |
ACE inhibitors n(%) | 42 (70%) | 35 (58.3%) | 37 (62.7%) | 114 (63.7%) | 0.41 |
ARBs n(%) | 5 (8.3%) | 6 (10%) | 8 (13.6%) | 19 (10.6%) | 0.64 |
Beta-blockers n(%) | 47 (78.3%) | 44 (73.3%) | 46 (78%) | 137 (76.5%) | 0.77 |
Alpha-blockers n(%) | 8 (13.3%) | 5 (8.3%) | 6 (10.2%) | 19 (10.6%) | 0.67 |
Centrally acting agents n(%) | 17 (28.3%) | 23 (38.3%) | 20 (33.9%) | 60 (33.5%) | 0.51 |
Non dihydropydine CCBs n(%) | 0 (0%) | 7 (11.7%) | 1 (1.7%) | 8 (4.5%) | <0.01 |
Dihydropydine CCBs n(%) | 24 (40%) | 27 (45%) | 38 (64.4%) | 89 (49.7%) | 0.02 |
Vasodilators n(%) | 15 (25%) | 14 (23.3%) | 15 (25.4%) | 44 (24.6%) | 0.96 |
Loop diuretics n(%) | 0 (0%) | 0 (0%) | 2 (3.4%) | 2 (1.1%) | 0.13 |
Abbreviations: PWV = pulse wave velocity; ACE = angiotensin converting enzyme; ARBs = angiotensin receptor blockers; CCBs = calcium channel blockers