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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Mol Psychiatry. 2015 Mar 10;21(1):118–125. doi: 10.1038/mp.2015.17

Figure 2.

Figure 2

By six weeks of age, canonical pathway alterations in Ptenm3m4/m3m4 cortex reflect those seen in transcriptome studies of human ASD. Canonical pathway analysis was performed using Ingenuity Pathway Analysis, the top 20 pathways implicated by upregulated genes are shown in purple (top), and those implicated by downregulated genes are shown in green (bottom). The axes indicate the significance of the pathway involvement, and lighter colored inset bars represent the pathway’s significance in the two-week old samples.