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. 2015 Aug 28;6(10):1020–1029. doi: 10.7150/jca.12733

Fig 1.

Fig 1

Effects of 10 or 100 μM zoledronate treatment on protein and mRNA expressions of DDR1 and DDR2. A) DDR1 and DDR2 expressions on western blotting at day 2 or 3 and representative western blots. Relative expressions of DDR1 and DDR2 were expressed as mean ± S.E.M. (n=4) * P ≤ 0.05, ** P ≤ 0.01, C versus Z100; + P ≤ 0.05, Z10 versus Z100; Paired Student's t-test. B) Immunopositivity scores of DDR1 and DDR2 and representative photomicrographs of PC3 cells stained with DDR1 or DDR2 antibodies immunocytochemically at day 3. Immunopositivity scores were expressed as mean ± S.E.M. (n=4) ** P ≤ 0.01, C versus Z100 Chi-square test. C) DDR1 and DDR2 mRNA expressions at day 3. mRNA fold changes were expressed as mean ± S.E.M. (n=4) * P ≤ 0.05, C versus Z100 Paired Student's t-test. C: Control, Z10: 10 μM zoledronate, Z100: 100 μM zoledronate.