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. 2015 Apr 22;72(19):3747–3768. doi: 10.1007/s00018-015-1908-0

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Summary of the enzymatic and chemical probing results for IFNA5 RNA (197–446). Mapping data are depicted upon common predicted secondary structure of different species using Centroid program http://www.ncrna.org/centroidfold/. Enzymatic cuts are showed as arrow heads (RNase T1), circles (RNase V1) and arrows (RNase A). The bases modified by DEPC are indicated by rhomboids and those cleaved by Pb²⁺ by stars. Strong cleavages are indicated by filled symbols and moderate ones by unfilled symbols. (+) and (−) enhanced or protected cleavage in MgCl₂. Numbers indicate nucleotide positions. D domain, l loop, PK possible pseudoknot. In blue, sequences participating in a predicted pseudoknot. Highlighted in gray are CAR-E sequences