Table 3.
Allele | Local Ancestry* | Case | Control | OR (95% CI) | P Value | Persistent | Resolved | OR (95% CI) | P Value |
---|---|---|---|---|---|---|---|---|---|
03:01 | 2 | 0.034 | 0.058 | 0.54 (0.39–0.75) | 2.1 × 10−4 | 0.034 | 0.031 | 1.10 (0.59–2.07) | 0.759 |
1 | 0.061 | 0.106 | 0.54 (0.34–0.860) | 0.009 | 0.028 | 0.078 | 0.29 (0.09–0.90) | 0.032 | |
0 | 0.173 | 0.095 | 2.18 (0.72–6.60) | 0.166 | 0.167 | 0.200 | –† | –† | |
Pint = 0.050 |
Pint = 0.146 |
||||||||
03:02 | 2 | 0.097 | 0.089 | 1.10 (0.88–1.38) | 0.415 | 0.085 | 0.137 | 0.56 (0.39–0.80) | 0.002 |
1 | 0.069 | 0.031 | 2.39 (1.36–4.18) | 0.002 | 0.056 | 0.108 | 0.44 (0.18–1.10) | 0.080 | |
0 | 0 | 0 | –† | –† | 0 | 0 | –† | –† | |
Pint = 0.009 |
Pint = 0.656 |
||||||||
11:01 | 2 | 0.191 | 0.130 | 1.73 (1.43–2.09) | 2.1 × 10−8 | 0.197 | 0.159 | 1.32 (0.95–1.83) | 0.100 |
1 | 0.094 | 0.060 | 1.68 (1.07–2.64) | 0.024 | 0.120 | 0.059 | 2.80 (1.01–7.74) | 0.048 | |
0 | 0.058 | 0.071 | 0.72 (0.16–3.31) | 0.678 | 0.083 | 0 | –† | –† | |
Pint = 0.583 |
Pint = 0.172 |
||||||||
12:01 | 2 | 0.083 | 0.043 | 2.08 (1.58–2.73) | 1.4 × 10−7 | 0.087 | 0.081 | 1.02 (0.67–1.56) | 0.915 |
1 | 0.057 | 0.027 | 2.31 (1.25–4.26) | 0.007 | 0.060 | 0.059 | 0.93 (0.33–2.63) | 0.889 | |
0 | 0.019 | 0.012 | 1.25 (0.10–15.69) | 0.861 | 0 | 0 | –† | –† | |
Pint = 0.939 | Pint = 0.970 |
Definition of abbreviations: CI, confidence interval; OR, odds ratio; Pint, Wald test P value for the allele-by–local ancestry interaction term(s).
Local African ancestry indicates the inferred number of African ancestral alleles present at the DRB1 locus for each subject.
Not estimable.