Skip to main content
. 2015 Aug;53(2):235–245. doi: 10.1165/rcmb.2014-0300OC

Figure 3.

Figure 3.

Extracellular ROS (superoxide [O2∙−]) in blood eosinophils. (A) Luminescence assay indicating a sharp increase in the O2∙− generation with PMA that was chloride channel 3 (CLC3) dependent. Control groups contained superoxide dismutase (SOD), no enhancer, or no PMA (n = 3). P < 0.05. (B) Eotaxin-1, eotaxin-3, TGF-β1, and TGF-β2 increased O2∙− release in a two-step process, which was lower in amplitude than PMA-induced O2∙− generation (n = 3). *P < 0.05 and ****P < 0.0001. NPPB, 5-nitro-2-(3-phenylpropylamino)benzoic acid.