Table 1. Nonsynonymous mutations identified in Chinese cervical cancer patients (No. = 105).

Amino acid change	Nucleotide change	No. of cases	Frequency of variants (%)	COSMIC reported	Function
p.E545K	c.1633G > A	59	7.7	Yes	Pathogenic
p.E542K	c.1624G > A	32	4.2	Yes	Pathogenic
p.H1047R	c.3140A > G	4	0.5	Yes	Pathogenic
p.M1043I	c.3129G > T	1	0.1	Yes	Pathogenic
p.E545A	c.1634A > C	1	0.1	Yes	Pathogenic
p.E545Q	c.1633G > C	1	0.1	Yes	Pathogenic
p.E545D	c.1635G > T	1	0.1	Yes	Pathogenic
p.H1047L	c.3140A > T	1	0.1	Yes	Pathogenic
p.Y1021C	c.3062A > G	1	0.1	Yes	Unknown
p.Y1021H	c.3061T > C	1	0.1	Yes	Unknown
p.G1049A	c.3146G > C	1	0.1	Yes	Unknown
p.R975K	c.2924G > A	1	0.1	No	Unknown
p.L523I	c.1567 T > A	1	0.1	No	Unknown