TABLE 2.
In vivo models | Animal species |
Features |
---|---|---|
Catheter-associated in vivo models, models utilizing amphogel coating on catheters and subcutaneous catheter models |
Rat, mouse, rabbit |
Rat and mouse models have advantage over rabbit models because they have a relatively low cost in setting, are easy to handle, and mimic the clinical conditions of rabbit models |
Denture-associated models |
Rat | Low cost, mimic clinical conditions |
Contact lens in vivo models |
Mouse | Low cost and clinically relevant |
Models using biotic surfaces such as oral cavity, oropharyngeal mucosa, tongue, vaginal mucosa |
Mouse | Low setting cost, mimic clinical conditions |