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. 2015 Sep 10;15:632. doi: 10.1186/s12885-015-1619-9

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© Trendowski et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Comparison of clinically approved chemotherapeutic agents and cytochalasin congeners against SKOV3 drug sensitive and SKVLB1 multidrug resistant human ovarian carcinomas. Abbreviations used are as follows: ADR (Adriamycin; doxorubicin), Tax (paclitaxel), VBL (vinblastine), CA (cytochalasin A), CB (cytochalasin B), DiHCB (21,22-dihydrocytochalasin B), CC (cytochalasin C), CD (cytochalasin D), CE (cytochalasin E), CH (cytochalasin H), and CJ (cytochalasin J). The concentration of each agent in nM needed to produce an IC₉₀ value at 96 h for either cell line is represented on a logarithmic scale. The resistance index (RI) of each compound against SKVLB1 is indicated in bold underneath the abbreviations