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. 2014 Nov 28;4(1):70–73. doi: 10.5455/jice.20141028021746

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Copyright: © SAGEYA

This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited.

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(a) Cross section of the liver of a control mouse, showing well-preserved liver plates and central vein (*). (b) Cross section of the liver of a mouse treated with Hibiscus rosa-sinensis leaf extract (800 mg/kg) by oral route for 14 days, showing dilated sinusoids and central vein (*). (c) Cross section of the kidney of a control mouse, showing conserved glomeruli (encircled areas) and tubules. (d) Cross section of the kidney of a mouse treated with H. rosa-sinensis leaf extract (800 mg/kg) by oral route for 14 days, showing disorganization of tubules (regular arrow) and glomerulus (encircled area) (haematoxylin-eosin)