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Cell viability assays of various anti-hypertensive agents with or without sunitinib at differing concentrations on A-498 (A) and 769-P (B) RCC cells and various anti-hypertensive agents with or without temsirolimus at differing concentrations on A-498 (C) and 769-P (D) RCC cells. The combination of sunitinib with captopril or lisinopril at 10 μM and above concentrations significantly decreased A-498 and 769-P RCC cell viability when compared to DMSO.
