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. 2015 Sep 11;12:137. doi: 10.1186/s12985-015-0363-8

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© Caraballo et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Survival after WNV inoculation. Nine week old Balb/c mice were IP inoculated with 10⁵ pfu of each WNV isolate, collected from either Vero (a) or C6/36 (b) cells. For each group, 10 mice were observed for morbidity and mortality for 28 days and the other 20 mice were sacrificed on days 2, 4, 6, 8, and 10 post-infection (4mice/day). Log rank test was performed to determine differences in survival rate between the PR isolates and the parental strain, NY99. When strains were Vero-derived, a trend towards a higher survival was observed in mice inoculated PR20wh when compared to NY99 (*p = 0.092). No significant differences in survival were observed, when mice were inoculated with C6/36-derived viruses. Only one experiment was performed