TABLE 1.
Combined fetal and neonatal cardiomyocyte data sets that are statistically best fit by linear regression, where y = slope (dPC) + intercept
| Parameter | Linear equation | R2 | Model comparison |
|---|---|---|---|
| Heart/body weight (g/kg) | −0.01408 dPC + 8.76 | 0.1593 | P > 0.22 |
| Cell length and width (μm) | |||
| LV quadrinucleate length | 0.7513 dPC + 2.438 | 0.7581 | — |
| LV quadrinucleate width | 0.1682 dPC − 6.51 | 0.4894 | — |
| RV quadrinucleate length | 0.6862 dPC + 14.68 | 0.5996 | — |
| RV mononucleate width | 0.05564 dPC + 6.154 | 0.6227 | P > 0.19 |
| RV binucleate width | 0.07102 dPC + 6.58 | 0.5019 | P > 0.18 |
| RV quadrinucleate width | 0.07132 dPC + 10.04 | 0.279 | — |
| Cell length:width ratio | |||
| LV mononucleate length:width | −0.02 dPC + 8.373 | 0.3704 | P > 0.65 |
| LV binucleate length:width | −0.03148 dPC + 10.91 | 0.4396 | P > 0.67 |
| LV quadrinucleate length:width | −0.009306 dPC + 7.583 | 0.05814 | — |
| RV quadrinucleate length:width | 0.01087 dPC + 4.107 | 0.09089 | — |
| Cell volume, μm3 | |||
| LV quadrinucleate volume | 801.4 dPC − 103,113 | 0.5799 | — |
| RV quadrinucleate volume | 376.4 dPC − 32,567 | 0.4573 | — |
| Myocyte and nuclei number (109) | |||
| LV neonatal period myocyte number | 9.721(10−5) dPC + 0.9023 | 0.0001083 | — |
| LV neonatal period nuclei number | 4.633(10−3) dPC + 0.9858 | 0.08577 | — |
| RV neonatal period myocyte number | 4.941(10−3) dPC − 0.2933 | 0.3001 | — |
| RV neonatal period nuclei number | 9.967(10−3) dPC − 0.6694 | 0.3878 | — |
| RV cell cycle activity (% of all myocytes) | −0.07452 dPC + 13.46 | 0.3653 | P > 0.26 |