Table 2.
Vitamin D binding protein, albumin, vitamin D and calcium concentrations before and after liver transplantation*
| Pretransplant (n = 202) |
Post-transplant (n = 155) |
P-value† | |
|---|---|---|---|
| Vitamin D binding protein (mg/dl) | 8.6 (5.5–14.5) | 23.8 (11.1–33.5) | <0.001 |
| Non-black race | 9.7 (6.7–14.8) | 23.8 (11.1–32.9) | <0.001 |
| Black race | 5.2 (3.8–10.6) | 23.8 (10.6–35.8) | <0.001 |
| Serum albumin, g/dl | 2.7 (2.2–3.3) | 3.8 (3.5–4.1) | <0.001 |
| Total 25(OH)D, ng/ml | 6.7 (3.7–13.7) | 27.4 (20.4–36.4) | <0.001 |
| Non-black race | 7.6 (4.3–14.2) | 28.3 (21.2–37.2) | <0.001 |
| Black race | 4.9 (1.5–10.7) | 24.4 (17–34) | <0.001 |
| Total 25(OH)D <20 ng/ml, n (%) | 170 (84) | 37 (23.9) | <0.001 |
| Non-black race | 132 (84) | 24 (19.8) | <0.001 |
| Black race | 38 (84) | 13 (38.2) | <0.001 |
| Free 25(OH)D, pg/ml | 5.8 (3.0–10.4) | 8.7 (6.3–15.4) | <0.001 |
| Non-black race | 6.1 (3.2–10.4) | 9.7 (6.4–15.6) | <0.001 |
| Black race | 4.5 (2.0–10.6) | 7.5 (5.2–12.4) | 0.51 |
| Percent free 25(OH)D (%) | 8.0 (5.2–10.8) | 3.1 (2.3–6.1) | <0.001 |
| Non-black race | 7.1 (5.0–9.7) | 3.1 (2.3–6.0) | <0.001 |
| Black race | 11.5 (6.4–15.3) | 3.2 (2.1–6.3) | <0.001 |
| Total 1,25(OH)2D, pg/ml | 11.4 (8.4–18.6) | 20.2 (8.6–31.1) | <0.001 |
| Total 1,25(OH)2D <20 pg/ml, n (%) | 155 (77) | 76 (49) | <0.001 |
| Free 1,25(OH)2D, fg/ml | 138 (87–214) | 98 (53–173) | <0.001 |
| Percent free 1,25(OH)2D | 1.2 (0.8–1.5) | 0.5 (0.4–0.9) | <0.001 |
| Serum calcium, mg/dl | 8.4 (8.1–9.0) | 9.1 (8.8–9.5) | <0.001 |
| Serum calcium (albumin corrected), mg/dl | 9.5 (9.0–9.9) | 9.3 (9.0–9.6) | 0.01 |
*
Continuous variables are presented as median (interquartile range).
†
Represents change pre- and post-transplantation.