Table 2.

Multiple logistic regression examining the association between complicated antimicrobial therapy and weight after adjusting for potential confounders (n = 421)

Predictor	Unadjusted OR	95% CI	Crude Pa	Adjusted OR	95% CI	Adjusted Pa
Weight
normal/overweight	reference			reference
obese	2.48	1.49–4.11	<0.001	2.01	1.72–3.45	0.01
underweight	1.28	0.57–2.85	0.55	1.26	0.54–2.95	0.59
Age (years)
17–34	reference			reference
35–64	2.90	0.96–8.71	0.06	2.07	0.66–6.47	0.21
65–79	2.76	0.92–8.30	0.07	1.93	0.62–6.06	0.26
80–100	1.58	0.48–5.22	0.46	1.25	0.36–4.37	0.73
Gender
male (versus female)	0.87	0.55–1.36	0.53
Ethnicity
white British	reference
white other	1.64	0.80–3.38	0.18
black other/Black Caribbean	1.17	0.45–3.09	0.75
black African	1.24	4.67–3.27	0.67
Indian/Pakistani/Bangladeshi	1.96	0.95–4.01	0.07
other Asian	1.83	0.70–4.74	0.22
other	0.70	0.26–1.91	0.49
Site
hospital 1	reference			reference
hospital 2	1.88	1.04–3.40	0.04	1.98	1.06–3.71	0.03
hospital 3	0.97	0.52–1.83	0.94	0.93	0.48–1.81	0.83
Reason for admission
Accident and emergency admission	reference
infection	1.39	0.81–2.38	0.24
planned surgery	1.51	0.77–2.96	0.23
planned procedure	1.04	0.21–5.20	0.96
other	1
Diabetes
yes (versus no)	1.26	0.76–2.08	0.37
Hypertension
yes (versus no)	1.46	0.93–2.31	0.10
Number of specific comorbidities	1.02	0.94–1.11	0.59
0	reference
1–3	1.04	0.48–2.26	0.92
4–6	1.69	0.81–3.54	0.16
≥7	1.04	0.40–2.70	0.93
Number of current medications
0–4	reference
5–7	1.25	0.53–2.98	0.611
8–10	1.74	0.78–3.86	0.175
≥11	2.03	0.95–4.36	0.067
Type of infection
infection other	reference			reference
hepatobiliary	1.85	0.76–4.50	0.17	1.73	0.68–4.38	0.25
pneumonia	2.54	1.38–4.66	0.003	2.61	1.37–4.97	0.003
surgical site	3.10	1.13–8.51	0.03	2.75	0.94–8.02	0.07
skin and soft tissue	2.35	1.13–4.87	0.02	2.43	1.12–5.29	0.03
urinary tract	0.92	0.38–2.22	0.85	0.96	0.38–2.42	0.93

^aStatistical significance is based on P < 0.05.