Table 2.
Clinical data of patients in the early and late TRT groups
| Time of TRT | Early TRT | Late TRT | ||
|---|---|---|---|---|
| Variables | (n = 89) | (n = 57) | χ2 | P |
| Gender | ||||
| Male | 60 (67.4%) | 43 (75.4%) | 1.076 | 0.354 |
| Female | 29 (32.6%) | 14 (24.6%) | ||
| Age | ||||
| ≤60 | 57 (64.0%) | 33 (57.9%) | 0.566 | 0.489 |
| >60 | 32 (36.0%) | 24 (42.1%) | ||
| Comorbidity | ||||
| Yes | 30 (33.7%) | 28 (49.1%) | 3.448 | 0.083 |
| No | 59 (66.3%) | 29 (50.9%) | ||
| Smoking | ||||
| Yes | 58 (65.2%) | 44 (77.2%) | 2.386 | 0.142 |
| No | 31 (34.8%) | 13 (22.8%) | ||
| Stage | ||||
| Ia–IIb | 16 (18.0%) | 4 (7.0%) | 3.531 | 0.083 |
| III | 73 (82.0%) | 53 (93.0%) | ||
| Response to 2–3 cycles of induction chemotherapy | ||||
| CR/PR | 67 (75.3%) | 47 (82.5%) | 1.045 | 0.412 |
| PD/SD | 22 (24.7%) | 10 (17.5%) | ||
| Irradiation techniques | ||||
| 3D-CRT | 44 (49.4%) | 38 (66.7%) | 4.189 | 0.041 |
| IMRT | 45 (50.6%) | 19 (33.3%) | ||
| Irradiation dose | ||||
| Total dose (Gy) | 50–60 | 50–66 | — | — |
| Fraction | 25–30 | 25–33 | ||
| Concurrent chemotherapy | ||||
| Yes | 38 (42.7%) | 7 (12.3%) | 15.076 | 0.000 |
| No | 51 (57.3%) | 50 (87.7%) | ||
| Prophylactic brain irradiation | ||||
| Yes | 38 (42.7%) | 14 (24.6%) | 4.983 | 0.033 |
| No | 51 (57.3%) | 43 (75.4%) | ||
| GTV (cm3) | ||||
| Median | 33.01 | 30.885 | — | — |
| Range | 0–287.9 | 0–422.3 |
3D-CRT, three-dimensional conformal radiation therapy; CR, complete remission; GTV, gross target volume; IMRT, intensity-modulated radiation therapy; PD, partial disease; PR, partial remission; SD, stable disease; TRT, thoracic radiotherapy.