Table 6.
Overall survival by different total score categories
| Variable | N | Events | Median years | Five-year survival % (95% CI) | log-rank P-value | Cox univariate hazard ratio (95% CI) | Cox univariate Wald P-value | Cox Univariate Score P-value |
|---|---|---|---|---|---|---|---|---|
| Total score category 1 | <0.0001 | <0.0001 | ||||||
| 32–36 | 30 | 29 (97%) | 0.5 | 3.6% (0.0%, 10.5%) | 33.46 (20.65, 54.21) | <0.0001 | ||
| 37–38 | 25 | 17 (68%) | 0.8 | 23.2% (4.3%, 42.2%) | 17.30 (9.81, 30.50) | <0.0001 | ||
| 39–41 | 119 | 81 (68%) | 1.5 | 19.0% (9.8%, 28.1%) | 12.46 (8.54, 18.16) | <0.0001 | ||
| 42–44 | 173 | 92 (53%) | 3.0 | 29.0% (20.1%, 37.9%) | 6.75 (4.68, 9.74) | <0.0001 | ||
| 45–47 | 290 | 105 (36%) | 5.3 | 50.5% (42.7%, 58.3%) | 3.87 (2.70, 5.54) | <0.0001 | ||
| 48–49 | 274 | 66 (24%) | NA | 72.1% (65.6%, 78.6%) | 1.98 (1.34, 2.91) | 0.0006 | ||
| 50–521 | 339 | 42 (12%) | NA | 84.7% (79.6%, 89.8%) | – | |||
| Total score category 2 | <0.0001 | <0.0001 | ||||||
| 32–35 | 21 | 20 (95%) | 0.5 | 5.3% (0.0%, 15.4%) | 68.65 (28.89, 163.11) | <0.0001 | ||
| 36–38 | 34 | 26 (76%) | 0.8 | 15.2% (1.7%, 28.7%) | 42.31 (18.31, 97.79) | <0.0001 | ||
| 39–41 | 119 | 81 (68%) | 1.5 | 19.0% (9.8%, 28.1%) | 25.45 (11.74, 55.19) | <0.0001 | ||
| 42–44 | 173 | 92 (53%) | 3.0 | 29.0% (20.1%, 37.9%) | 13.81 (6.40, 29.79) | <0.0001 | ||
| 45–47 | 290 | 105 (36%) | 5.3 | 50.5% (42.7%, 58.3%) | 7.92 (3.68, 17.02) | <0.0001 | ||
| 48–50 | 498 | 101 (20%) | NA | 75.7% (71.0%, 80.5%) | 3.39 (1.58, 7.29) | 0.0018 | ||
| 51–521 | 115 | 7 (6%) | NA | 94.1% (89.0%, 99.2%) | – | |||
| Total score category 3 | <0.0001 | <0.0001 | ||||||
| 32–35 | 21 | 20 (95%) | 0.5 | 5.3% (0.0%, 15.4%) | 67.82 (28.55, 161.15) | <0.0001 | ||
| 36–39 | 75 | 53 (71%) | 1.1 | 21.0% (9.7%, 32.3%) | 28.78 (13.06, 63.42) | <0.0001 | ||
| 40–43 | 182 | 112 (62%) | 2.0 | 18.6% (10.7%, 26.4%) | 19.38 (9.02, 41.65) | <0.0001 | ||
| 44–47 | 359 | 139 (39%) | 4.4 | 48.3% (41.5%, 55.2%) | 8.61 (4.03, 18.39) | <0.0001 | ||
| 48–50 | 498 | 101 (20%) | NA | 75.7% (71.0%, 80.5%) | 3.39 (1.58, 7.29) | 0.0018 | ||
| 51–521 | 115 | 7 (6%) | NA | 94.1% (89.0%, 99.2%) | – | |||
| Total score category 4 | <0.0001 | <0.0001 | ||||||
| 32–37 | 44 | 37 (84%) | 0.6 | 8.3% (0.0%, 17.1%) | 29.06 (18.49, 45.66) | <0.0001 | ||
| 38–43 | 234 | 148 (63%) | 1.9 | 20.0% (13.0%, 27.0%) | 9.97 (7.05, 14.09) | <0.0001 | ||
| 44–47 | 359 | 139 (39%) | 4.4 | 48.3% (41.5%, 55.2%) | 4.21 (2.98, 5.95) | <0.0001 | ||
| 48–49 | 274 | 66 (24%) | NA | 72.1% (65.6%, 78.6%) | 1.98 (1.34, 2.91) | 0.0006 | ||
| 50–521 | 339 | 42 (12%) | NA | 84.7% (79.6%, 89.8%) | – |
1
Reference group.