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. 2015 Sep 11;10(9):e0137745. doi: 10.1371/journal.pone.0137745

Fig 3. OS nature of skeletal tumors in Ptprz1-deficient Trp53-heterozygous mice.

Fig 3

(A) Von Kossa/Van Gieson staining of undecalficied sections confirms that the tumors contain mineralized matrix (stained black). (B) Toluidine blue staining demonstrating dark blue staining of cartilage areas and light blue staining of the tumors. (C) Higher magnification images reveal that the tumors represented bony tissue with osteocytes embedded into the mineralized matrix.