Table 3. Non-Cardiac Hypoxemia Diseases.

No	Diagnosis	Risk factor	PO1 foot, PO2 foot	Age of screening (hours of life)	Routine physical examination	Echocardiography	Investigation	Treatment	Outcome
1	Neonatal sepsis	Risk factor of sepsis +	86%, 84%	16	Normal	Small PFO/PDA	Streptococcus pneumonia (blood culture)	Antibiotics	Alive
2	Neonatal sepsis	Risk factor of sepsis +	92%, 93%	21	Normal	Small muscular VSD	Sterile blood culture	Antibiotics	Alive
3	Down syndrome with primary PPHN	Nil	87%, 88%	6	Normal	High Tricuspid regurgitation jet 60mmHg, large PDA 5.7mm	CXR: normal Sterile blood culture	Ventilated Inhaled nitric oxide Inotropic support Antibiotics	Alive
4	PPHN with polycythemia	Nil	87%, 81%	8	Normal	Small PFO/PDA	Hematocrite: 0·8	Partial exchange at 10 hours of life	Alive
5	TTN	Nil	93%, 95%	22	Normal	Small PFO/PDA	CXR: normal	Oxygen support	Alive
6	TTN	Nil	82%, 83%	20	Normal	Small PFO/PDA	CXR: normal	Oxygen support	Alive
7	TTN	Nil	89%, 86%	24	Normal	Small apical VSD, small PDA	CXR: normal	Oxygen support	Alive
8	TTN	Nil	87%, 90%	25	Normal	Small PFO/PDA	CXR: normal	Oxygen support	Alive
9	Congenital pneumonia	Risk factor of sepsis +	86%, 86%	14	Normal	Mid muscular VSD 1.5mm	CXR: small spontaneous pneumothorax right lung	Oxygen support Antibiotics	Alive
10	Congenital pneumonia	Risk factor of sepsis +	82%, 85%	7	Normal	Small apical VSD	CXR: bilateral diffuse patchy opacities	Oxygen support Antibiotics	Alive
11	Meconium aspiration syndrome	Light meconium stained liquor delivery	92%, 93%	5	Normal	Small PFO/PDA.	CXR: bilateral diffuse patchy opacities	Oxygen support Antibiotics	Alive
12	Meconium aspiration syndrome	meconium stained liquor delivery	84%, 86%	5	Normal	Atrial septal defect (ASD) 4 mm, PDA 3 mm. Tricuspid regurgitation jet 30mmHg	CXR: bilateral diffuse patchy opacities	Ventilated at 12 hours of life Antibiotics	Alive
13	Hypoplastic right lung with VACTERL association	Nil	92%, 94%	13	Right forearm deformity	Mesocardia, small PDA	Computerized tomograms of thorax: right lung hypoplasia. Skeletal survey: absent right radius, T6 hemivetebra Ultrasound of kidney: bilateral horseshoe kidneys	Continuous bilevel positive airway pressure (BIPAP)	Alive

PO1, first pulse oximetry reading; PO2, second pulse oximetry reading; SpO2, oxygen saturation; PFO, patent foramen ovale; PDA, patent ductus arteriosus; CXR, chest x-ray; VSD, ventricular septal defect; PPHN, persistent pulmonary hypertension of newborn; TTN, transient tacypnoea of newborn; VACTERL, vertebral anomalies, anal atresia, cardia defects, tracheoesophageal fistula and or esophageal atresia, renal and radial anomalies, and limb defects