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. 2015 Apr 15;2(2):ofv052. doi: 10.1093/ofid/ofv052

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Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 3. — Correlations with vaccine antibody response. Antibody to A and C, H3N2 and B and D, H1N1 were assessed from serum samples taken at prevaccination and 28 days postvaccination by A and B, HI (n = 88) and C and D, microneutralization ([MN] n = 90). Antibody levels were plotted by age, and correlations were calculated to determine the effect of age on preexisting and postvaccination antibody titers. The correlation coefficient and P value are presented for correlations with age. E, The influence of preexisting, cross-reactive antibody to H3N2 () and H1N1 () on the postvaccination, day 28 response was also determined. The correlation of pre- and postvaccination antibody responses to H1N1 () and H3N2 () are depicted. The correlation coefficient and P value are presented for prevaccination H1N1 () and H3N2 () correlations with the postvaccination titers. HI, hemagglutination inhibition.

Inline graphic — Correlations with vaccine antibody response. Antibody to A and C, H3N2 and B and D, H1N1 were assessed from serum samples taken at prevaccination and 28 days postvaccination by A and B, HI (n = 88) and C and D, microneutralization ([MN] n = 90). Antibody levels were plotted by age, and correlations were calculated to determine the effect of age on preexisting and postvaccination antibody titers. The correlation coefficient and P value are presented for correlations with age. E, The influence of preexisting, cross-reactive antibody to H3N2 () and H1N1 () on the postvaccination, day 28 response was also determined. The correlation of pre- and postvaccination antibody responses to H1N1 () and H3N2 () are depicted. The correlation coefficient and P value are presented for prevaccination H1N1 () and H3N2 () correlations with the postvaccination titers. HI, hemagglutination inhibition.