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A) At 16 weeks, the aortic sinus plaque area in the IL-1Ra+/−/apoE−/− mice was significantly larger than in the IL-1Ra+/+/apoE−/− mice (P <0.01). B) There was no significant difference in plaque area between the groups at 32 weeks.
apoE = apolipoprotein E; IL-1Ra = interleukin-1 receptor antagonist
P <0.05 was considered statistically significant.
