Table 2. Acinetobacter baumannii ATCC17978 genes indicated by microarray analysis as being upregulated after exposure to oleanolic acid.
| Locus tag | Gene | Protein name | Fold change |
|---|---|---|---|
| Oxidative stress, DNA repair | |||
| A1S_0617 | ohr | Predicted redox protein, regulator of disulfide bond formation | 1.658 |
| A1S_2717 | Dihydrolipoamide dehydrogenase | 1.657 | |
| A1S_0315 | DNA repair system | 1.629 | |
| A1S_0159 | gpx | Glutathione peroxidase | 1.597 |
| A1S_2664 | groEL | 60 kDa Chaperonin | 1.518 |
| Cell envelope biogenesis, outer membrane | |||
| A1S_0041 | des6 a | Putative linoleoyl-CoA desaturase | 1.673 |
| A1S_0058 | gtfs a | Glycosyltransferase | 1.891 |
| A1S_3398 | murl a | Glutamate racemase | 1.675 |
| A1S_0311 | ybaW a | Putative acyl-CoA thioesterase II | 1.581 |
| A1S_0431 | htrB a | Lipid A biosynthesis lauroyl acyltransferase | 1.503 |
| A1S_2078 | yhbS a | Predicted acetyltransferase | 1.504 |
| A1S_3406 | hutU a | Urocanate hydratase | 1.807 |
| A1S_0494 | gtfs | Putative glycosyl transferase | 1.623 |
| A1S_2016 | nucD | Lysozyme, Phage-related lysozyme | 1.701 |
| A1S_2089 | yehB a | Fimbrial usher protein | 1.561 |
| A1S_0232 | Type 4 fimbriae expression regulatory protein | 1.509 | |
| A1S_0329 | pilB a | Type 4 fimbrial biogenesis protein | 1.552 |
| Energy metabolism | |||
| A1S_1023 | adk | Adenylate kinase | 2.416 |
| A1S_0152 | atpH | Membrane-bound ATP synthase F1 sector, | 1.675 |
| A1S_0080 | fabB a | Beta-ketoacyl-ACP synthase I | 1.663 |
| A1S_0155 | atpD | ATP synthase subunit beta | 1.626 |
| A1S_0151 | atpE | Membrane-bound ATP synthase F0 sector | 1.539 |
| A1S_0153 | atpA | ATP synthase subunit alpha | 1.513 |
| A1S_1443 | tauB | Taurine ATP-binding transport system component | 1.506 |
| A1S_0587 | panC | Pantothenate synthetase | 1.523 |
| Transport, transferase | |||
| A1S_0092 | foxA a | Putative ferric siderophore receptor protein | 1.743 |
| A1S_0538 | macA a | Putative RND drug transporter | 1.540 |
| A1S_0651 | traB | TraB protein | 1.626 |
| A1S_0029 | ssuA a | ABC-type nitrate/sulfonate/bicarbonate transport system | 1.514 |
| A1S_0922 | hmt-1 a | Putative homocysteine S-methyltransferase protein | 1.667 |
| A1S_3198 | rlmA1 a | 23S Ribosomal RNA G745 methyltransferase | 1.542 |
| A1S_3244 | thrB | Homoserine kinase | 1.532 |
a Gene names derived from the KEGG orthology; the similarity to these genes is more than 70%