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. 2015 Mar 18;50(3):194–198. doi: 10.1310/hpj5003-194

Table 1. AD regimen1–3.

Drug Dose Route of administration Administered on day(s) Total dose/cycle
Doxorubicin 15 mg/m2 CIVI 1, 2, 3,4 60 mg/m2
Dacarbazine 187.5 mg/m2 CIVI 1, 2, 3,4 750 mg/m2
Cycle repeats: Every 21 days
Variations

  1. Doxorubicin 60 mg/m2 IV, dacarbazine 750 mg/m2 IV day 1, repeat every 21 days.2

  2. Doxorubicin 15 mg/m2 CIVI, dacarbazine 250 mg/m2 CIVI days 1 through 4, repeat every 21 days.3

  3. Doxorubicin 60 mg/m2 IV day 1, dacarbazine 250 mg/m2 CIVI days 1 through 5, repeat every 21 days.1

Note: CIVI = continuous (24-hour) intravenous infusion; IV = intravenous.