Table 1.
Baseline characteristics of the study groups
| No SRBD (AHI ≥5 events/hour) |
Mild SRBD (AHI 5–15 events/hour) |
Moderate to severe SRBD (AHI >15 events/hour) |
P-value | |
|---|---|---|---|---|
| n | 11 | 19 | 18 | |
| Age (years) | 80±5 | 82±4 | 81±8 | 0.51 |
| Body mass index (kg/m2) | 25±3 | 26±6 | 26±5 | 0.85 |
| CAD (%) | 82 | 63 | 79 | |
| Atrial fibrillation (%) | 36 | 39 | 47 | |
| Glomerular filtration rate (mL/min) | 67±28 | 60±20 | 55±19 | 0.34 |
| Systolic blood pressure (mmHg) | 156±20 | 143±28 | 147±21 | 0.38 |
| Diastolic blood pressure (mmHg) | 74±15 | 66±8 | 66±13 | 0.21 |
| Mean arterial pressure (mmHg) | 101±16 | 91±13 | 93±14 | 0.23 |
| NTproBNP (pg/mL) | 986±862 | 2,337±2,758 | 4,270±4,421 | 0.10 |
| FEV1 (L) | 1.77±0.80 | 1.48±0.55 | 1.64±0.55 | 0.46 |
| FEV1 predicted (%) | 79±25 | 75±20 | 81±27 | 0.79 |
| AHI (per hour) | 3±1 | 10±3 | 27±11 | |
| Central apnea index (per hour) | 0.7±1.2 | 0.3±0.9 | 1.4±2.4 | |
| Obstructive apnea index (per hour) | 1.8±1.2 | 8.1±3.8 | 21.1±13.4 | |
| Mean minimal oxygen saturation (%) | 89±2 | 89±3 | 88±5 | 0.60 |
| Time below 90% (minutes) | 6.8±7.0 | 30.8±70.5 | 33.8±28.3 | 0.37 |
Abbreviations: AHI, apnea–hypopnea index; SRBD, sleep-related breathing disorders; CAD, coronary artery disease; NTproBNP, n-terminal of the prohormone brain natriuretic peptide; FEV1, forced expiratory volume after 1 second.