Table 1.
Factors related to HBV reactivation
| Univariate analysis
|
Multivariate analysis
|
||||
|---|---|---|---|---|---|
| Patients with HBV reactivation (n=23) | Patients without HBV reactivation (n=86) | P-value | OR (95% CI) | P-value | |
| Age (years) | 52.9±1.7 | 56.3±1.0 | 0.122 | 0.95 (0.89–1.00) | 0.90 |
| Sex (M:F) | 21:2 | 71:15 | 0.518 | 0.36 (0.05–2.43) | 0.292 |
| HBeAg (positive:negative) | 5:18 | 4:82 | 0.019 | 7.41 (1.53–35.91) | 0.013 |
| AFP (ng/mL) | 3,238.1±2,605 | 583.9±113.2 | 0.001 | 1.00 (1.00–1.00) | 0.522 |
| ALT (IU/L) | 52.8±8.2 | 38.0±3.5 | 0.2 | 1.02 (0.99–1.05) | 0.098 |
| AST (IU/L) | 59.2±10.3 | 62.5±14.5 | 0.807 | 0.99 (0.97–1.01) | 0.365 |
| ALB (g/L) | 48.8±0.9 | 41.9±0.7 | 0.383 | 0.96 (0.88–1.04) | 0.277 |
| Tbil (µmol/L) | 21.0±2.6 | 19.8±1.0 | 0.086 | 0.99 (0.95–1.04) | 0.773 |
| ALP (IU/L) | 113.9±9.8 | 119.5±7.3 | 0.195 | 0.99 (0.98–1.00) | 0.581 |
| GGT (IU/L) | 143.6±34.8 | 123.4±16.8 | 0.728 | 1.00 (0.99–1.00) | 0.896 |
Abbreviations: HBV, hepatitis B virus; OR, odds ratio; CI, confidence interval; M, male; F, female; Tbil, total bilirubin; ALT, alanine aminotransferase; AFP, α- fetoprotein; AST, aspertate aminotransferase; ALB, albumin; ALP, alkaline phosphatase; GGT, glutamine transpeptidase; HBeAg, hepatitis B e antigen.