Fig 5. Virulence of the Pbccp-aRNA mutant in the liver and spleen of infected BALB/c mice.

Colony forming units recovered from the spleen (A) and liver (B) of mice infected with P. brasiliensis wild type (WT), P. brasiliensis containing the empty vector (EV) and the silenced mutant Pbccp-aRNA1. The experiments were performed in biological triplicates. Error bars represent the standard deviation from biological replicates, while * represents p-values < 0.01.