Figure 1. A schematic representation of the CB2 receptor.
CB2 consists of an extracellular N-terminus, 2 extracellular loops (EC1-3), 7 transmembrane domains (TM1-7), 3 intracellular loops (IC1-3) and an intracellular C-terminal domain, which is involved in signal transduction. The arrows indicate the protein segment that is deleted in Cnr2tmZim mice.