Table 1.
CB1 and CB2 agonist properties of cannabinoids
| Cannabinoids | CB1 | CB2 | Type | Cannabinoid Group |
|---|---|---|---|---|
| THC | Partial agonist | Partial agonist | natural | Classical |
| HU-210 | Full agonist | Full agonist | synthetic | Classical |
| CP-55940 | Full agonist | Full agonist | synthetic | Non-classical |
| R-(+)-WIN55,212–2 | Full agonist | Full agonist | natural | Aminoalkylindole |
| AEA | Partial agonist | Partial agonist | natural | Eicosanoid |
| 2-AG | Full agonist | Full agonist | natural | Eicosanoid |
| R(+)-methanandamide | Partial agonist | Partial agonist | synthetic | Eicosanoid |
| ACEA | Partial agonist | Partial agonist | synthetic | Eicosanoid |
| HU-308 | Weak CB1 binding | Selective agonist | synthetic | Non-classical |
| JWH-133 | Weak CB1 binding | Selective agonist | synthetic | Classical |
| JWH-015 | Weak CB1 binding | Selective agonist | synthetic | Aminoalkylindole |
| AM124 | Weak CB1 binding | Selective agonist | synthetic | Aminoalkylindole |