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. 2015 Sep 11;10(9):e0137721. doi: 10.1371/journal.pone.0137721

Table 1. Baseline demographics, clinical characteristics, and comorbidities of 69 patients with sepsis.

Survivors (n = 38) Nonsurvivors (n = 31) p-value
Age, years, mean (SD) 58.3 (16.7) 60.1 (17.5) 0.659
Male sex, n (%) 27 (71.1) 24 (77.4) 0.552
APACHE II score, median (IQR) 16.5 (11.8–22.3) 27.0 (17.0–36.0) 0.000 a
Infection sources, n (%)
    Pulmonary 23 (60.5) 24 (77.4) 0.195
    Abdominal 11 (28.9) 3 (9.7) 0.071
    Intracranial 1 (2.6) 3 (9.7) 0.319
    Skin and soft-tissue 0 (0) 1 (3.2) 0.449
    Urinary tract 1 (2.6) 0 (0) 1.000
    Bloodstream 2 (5.3) 0 (0) 0.498
Comorbidities, n (%)
    Diabetes 5 (13.2) 6 (19.4) 0.525
    Cardiovascular disease 4 (10.5) 4 (12.9) 1.000
    Hypertension 6 (15.8) 5 (16.1) 1.000
    Cerebrovascular disease 2 (5.3) 3 (9.7) 0.651
    Chronic pulmonary disease 5 (13.2) 3 (9.7) 0.722
    Post-operation 6 (15.8) 5 (16.1) 1.000
    Trauma 6 (15.8) 2 (6.5) 0.281
    Others 18 (47.4) 16 (51.6) 0.811
Length of ICU stay, days, mean (SD) 10.7 (8.3) 17.5 (27.4) 0.193
Length of hospital stay, days, mean (SD) 24.4 (14.8) 23.7 (32.0) 0.907
SOFA score, median (IQR) 6 (4–8) 10 (6–14) 0.001

APACHE II = Acute Physiology and Chronic Health Evaluation II, SOFA = Sepsis-related Organ Failure Assessment.

The p-values for age were calculated using the t-test, and those for the APACHE II scores and SOFA score were calculated using the Mann-Whitney U test. Fisher’s exact tests were applied for the categorical variables. A p-value < 0.05 was considered to be statistically significant.

IQR = inter-quartile range, SD = standard deviation.

a p = 0.000433.