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. Author manuscript; available in PMC: 2015 Sep 11.
Published in final edited form as: Int J Numer Method Biomed Eng. 2013 Jun 24;29(10):1104–1133. doi: 10.1002/cnm.2565

Table I.

Chemo-electrical material parameters of human ventricular cardiomyocyte.

sodium related potassium related calcium related calciumsr related

concentrations cNa0 = 140 mM cK0 = 5.4 mM cCa0 = 2 mM -

maximum currents
INaCamax=1000pA/pF
INaCamax=1000pA/pF
INaKmax=1.362pA/pF
INaKmax=1.362pA/pF
Ileakmax=0.08s1
Ileakmax=0.08s1
Iupmax=0.425mM/s
Iupmax=0.425mM/s
Irelmax=8.232mM/s
Irelmax=8.232mM/s

maximum conductances
CNamax=14.838nS/pF
CK1max=5.405nS/pF
CCaLmax=0.175mm3/[μFs]
CbNamax=0.00029nS/pF
CKrmax=0.0096nS/pF
CbCamax=0.000592nS/pF
CKs,epimax=0.245nS/pF
CpCamax=0.825nS/pF
CKs,endomax=0.245nS/pF
CKs,Mmax=0.062nS/pF
CpKmax=0.0146nS/pF
Ct0,epimax=0.294nS/pF
Ct0,endomax=0.073nS/pF
Ct0,Mmax=0.294nS/pF

half saturation constants cCaNa = 1.38 mM cCaNa= 1.38 mM
cCNa = 87.50 mM cNaCa = 87.50 mM
cKNa = 1.00 mM cKNa = 1.00 mM cpCa = 0.0005 mM
cNaK = 40.00 mM cNaK == 410.0.000mM cup = 0.00025 mM cup = 0.00025 mM
crel = 0.25 mM crel =0.25 mM
cbuf = 0.001 mM
cbufsr=0.3mM

other parameters
kNaCasat=0.10
pKNa = 0.03 γrel = 2 γrel = 2
γNaCa= 2.50 γtot = 0.15 mM
ctotsr=10mM
γ = 0.35

gas constant R =8.3143 J K−1 mol−1 temperature T =310 K cytoplasmic volume V =16404μm3
Faraday constant F =96.4867 C/mmol membrane capacitance C =185 pF sarcoplasmic reticulum volume Vsr= 1094μm3