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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Am Soc Echocardiogr. 2015 May 2;28(9):1114–1121. doi: 10.1016/j.echo.2015.04.001

Table 3.

Results of multivariable Cox proportional hazards models with time to first coronary heart disease event as outcome. The hazards ratios (HR) and the 95% confidence intervals (Lower 95% and Upper 95%) of the basic model or to the left and for the addition of common carotid artery intima-media thickness variables to the right.

Variables Risk factors Risk factors and near wall IMT* Risk factors and far wall IMT* Risk factors and mean of the far wall and near wall IMT*
HR Lower 95% Upper 95% HR Lower 95% Upper 95% HR Lower 95% Upper 95% HR Lower 95% Upper 95%
Age (years) 1.05 1.04 1.06 1.05 1.04 1.06 1.04 1.03 1.05 1.04 1.03 1.06
Sex (men) 2.06 1.68 2.54 2.06 1.67 2.54 1.97 1.60 2.43 1.98 1.61 2.45
Race-Ethnicity
White (referent) ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- -----
Chinese 0.58 0.41 0.80 0.58 0.41 0.80 0.59 0.42 0.82 0.60 0.43 0.83
African American 0.78 0.62 0.99 0.78 0.62 0.99 0.78 0.62 0.98 0.76 0.61 0.96
Hispanic 0.77 0.61 0.98 0.77 0.61 0.98 0.79 0.62 1.00 0.78 0.61 0.99
Diabetes (yes) 1.85 1.49 2.30 1.85 1.49 2.30 1.79 1.44 2.22 1.79 1.44 2.22
Smoker (yes) 1.66 1.29 2.14 1.66 1.28 2.14 1.65 1.28 2.12 1.64 1.27 2.11
Systolic blood pressure* 1.29 1.18 1.41 1.29 1.18 1.41 1.24 1.14 1.36 1.25 1.14 1.37
HDL cholesterol* 0.85 0.76 0.95 0.85 0.76 0.95 0.86 0.76 0.96 0.86 0.76 0.96
Total cholesterol* 1.14 1.04 1.25 1.14 1.04 1.25 1.13 1.03 1.25 1.14 1.03 1.25
Intima-media thickness* 1.01† 0.92 1.11 1.21 1.13 1.30 1.17 1.08 1.28
*

standardized values: units of 21.5 mmHg for systolic pressure, 35.6 mg/dL for total cholesterol, 14.8 mg/dL for HDL cholesterol. 0.19 mm for near wall intima media thickness, 0.21 mm for far wall intima media thickness, and 0.18 mm for mean of near and far wall intima media thickness

All variables are significantly associated with coronary heart disease outcomes except for the near wall intima media thickness.