Table 3.
General Linear Models testing relationship of TLR-4 inflammatory response and covariates with BPI symptom scores.
| Outcome Measure | Predictor | B. | S.E. | F1,65 | 95% CI | p |
|---|---|---|---|---|---|---|
| Pain Severity (BPI) | ||||||
| TLR-4 inflammatory response | .503 | .197 | 6.53 | .109,.896 | .013 | |
| Comorbid condition | .204 | .429 | .23 | −1.063, .655 | .64 | |
| Use of SSRI/SNRI | −.156 | .615 | .06 | −1.075, 1.386 | .97 | |
| PANAS negative affect | .096 | .025 | 14.83 | .046,.145 | <.01 | |
| Pain Interference (BPI) | ||||||
| TLR-4 inflammatory response | .567 | .278 | 4.17 | .012, 1.123 | .046 | |
| comorbid condition | .200 | .607 | .50 | −1.414, 1.014 | .74 | |
| Use of SSRI/SNRI | −.028 | .832 | .01 | −1.635, 1.691 | .97 | |
| PANAS negative affect | .171 | .035 | 23.67 | .101,.241 | <.01 |
BPI= Brief Pain Inventory. IL-6=Interleukin-6. PANAS=Positive and Negative Affect Scale. TLR=Toll-Like Receptor.