Table 3.

OLS regressions of the effect of depression score^a on cytokine response to ex vivo antigen stimulation. Standardized β's are shown (95% CIs for β_{Depression score}) controlling for age, sex, BMI and unstimulated serum cytokine concentration^b,c.

	TNF-α		IL-1β		IL-6
Parameter	LPS-stimulated	PHA-stimulated	LPS-stimulated	PHA-stimulated	LPS-stimulated	PHA-stimulated
Depression score	0.09 (−0.12-0.30)	0.16^ (−0.04-0.36)	0.32*** (0.13-0.51)	0.41*** (0.23-0.60)	0.21* (0. 01-0.43)	0.27** (0.07-0.47)
Controls
Age (years)	0.04	0.09	−0.08	−0.05	−0.06	0.06
Sex=female	−0.20	−0.23	−0.74***	−0.54**	−0.30^	−0.49**
BMI (kg/m2)	0.01	0.06	0.08	0.13	0.05	0.02
log(unstimulated serum cytokine concentration)	0.15	0.24*	−0.05	−0.08	−0.03	−0.05
Adjusted R2	<0.01	0.06	0.13	0.15	<0.01	0.06
N individuals	117	121	119	123	118	124

^***p≤0.001

^**p≤0.01

^*p≤0.05

^{^}p≤0.1

^aSummed 16 items

^b95% CIs for controls are not included due to space limitations

^cCytokine concentrations (unstimulated and stimulated) are logged to normalize distributions