Table 2.
Pro- and anti-inflammatory cytokine (pg/ml) levels (mean ± SE) and cortisol area under the curve (AUC) during the prenatal period through 6-months postpartum
Prenatal | Day 7 | Day 14 | Month 1 | Month 2 | Month 3 | Month 6 | |
---|---|---|---|---|---|---|---|
IL-6 | 1.86 (±.20) | 3.08** (±.28) | 1.85 (±.19) | 1.93 (±.21) | 1.82 (±.28) | 2.06* (±.49) | 1.73* (±.18) |
IFNγ | 1.71 (±.16) | 3.12** (±.49) | 2.37** (±.27) | 3.01** (±.38) | 2.12** (±.20) | 2.88** (±.58) | 2.46** (±.36) |
TNFα | 5.49 (±.29) | 6.27** (±.37) | 6.22** (±.34) | 6.84** (±.37) | 6.30** (±.35) | 6.85** (±.42) | 6.95* (±.52) |
IL-1β | 0.52 (±.07) | 1.06** (±.39) | 0.76** (±.13) | 1.38** (±.49) | 0.90* (±.21) | 0.78* (±.14) | 0.81* (±.18) |
IL-10 | 7.32 (±1.95) | 9.72** (±2.96) | 10.19* (±4.13) | 10.50 (±3.21) | 11.70 (±4.73) | 10.87 (±3.66) | 11.81 (±3.87) |
IL-8 | 4.10 (±.37) | 6.02** (±.22) | 6.52** (±.75) | 5.99** (±.79) | 5.94** (±1.08) | 5.69** (±.76) | 5.66** (±1.02) |
Cortisol AUC | 3.29 (±.09) | 2.35** (±.08) | 1.96** (±.07) | 1.68** (±.06) | 1.72** (±.14) | 1.60** (±.05) | 1.64** (±.09) |
For comparisons against prenatal levels:
indicates p≤0.05,
indicates p≤0.005