Table 1. Characteristics of LF and HF-fed Agtfl/fl and AgtAlb male mice after 16 weeks of diet.
Characteristics | LF Diet | HF Diet | ||
---|---|---|---|---|
| ||||
Agtfl/fl | AgtAlb | Agtfl/fl | AgtAlb | |
Body Weight | 32.0±0.8 | 31.5±1.0 | 45.5±1.9* | 42.8±2.3* |
Liver | 1.25±0.04 | 1.28±0.07 | 2.30±0.25* | 1.92±0.28* |
Kidney | 0.35±0.01 | 0.32±0.01 | 0.42±0.01* | 0.34±0.01† |
Heart | 0.141±0.007 | 0.118±0.004† | 0.159±0.005* | 0.139±0.010*,† |
Visceral adipose | 1.25±0.15 | 1.23±0.14 | 2.46±0.14* | 2.34±0.19* |
Subcutaneous | 0.49±0.06 | 0.46±0.05 | 1.78±0.20* | 1.61±0.21* |
BAT | 0.14±0.01 | 0.14±0.01 | 0.23±0.02* | 0.23±0.02* |
Plasma
Aldosterone (pg/ml) |
1.17 ± 0.30 | 0.71 ± 0.19† | 1.18 ± 0.04 | 0.42 ± 0.02† |
Body and tissue weights are in grams. Data are mean ± SEM.
P<0.05 compared to LF within genotype.
P<0.05 compared to Agtfl/fl within diet group, N=14-21/group. BAT, Brown Adipose Tissue. For plasma aldosterone, N=6/group.