. 2015 Sep;40(5):454–460.

Table 3.

Comparison of different studies about K-ras gene status in CRC in different parts of Iran

Study	Year	Method	Sample size	Mutation prevalence (%)	Most common substitution
Shemirani et al.⁹	2011	Codon 1213	48 CRC	12.5	12G→A (GGT>GAT)
Shemirani et al.⁹	2011	PCRsequencing			(Gly→Asp)
Sobhani et al.¹⁰	2010	Codon 1213	59	20.3	12G→A (GGT>GAT)
Sobhani et al.¹⁰	2010	PCRsequencing			(Gly→Asp)
Bishehsari et al.⁸	2006	Codon12, 13, 61	182	37.4	12G→A (GGT>GAT)
Bishehsari et al.⁸	2006	PCRsequencing			(Gly→Asp)
Current study	2013	PCRsequencing	100	32	12G>C