Fig. 14.

M1 and S1 control the gain of suppressed firing rate modulations in infragranular layers. A: prediction of neural state maps for suppressed firing rate modulations in control conditions using the neural state maps from M1 inactivation (open), S1 inactivation (shaded), or from both combined (solid) indicated that a large increase in prediction can be achieved by combining both conditions. B: prediction of neural state maps for facilitated firing rate modulations in control conditions using the neural state maps from M1 inactivation (open), S1 inactivation (shaded), or from both combined (solid) indicated that only a small increase in prediction can be achieved by combining both conditions (because each condition alone was already a good predictor of neural state maps in control conditions). C: control (gray) and predicted values (blue) for suppressed firing rate modulations during the task. Note that by averaging the effects of M1 and S1 inactivation an overall very good prediction of the fraction of suppressed firing rate modulations in control conditions can be obtained. This suggests that ipsilateral M1 and contralateral S1 control the gain of suppressed firing rate modulations during a trial. D: control (gray) and predicted values (red) for facilitated firing rate modulations during the task. Note that facilitated firing rate modulations from M1 or S1 inactivation conditions alone were already good predictors of neuronal firing rate modulations occurring in control conditions, and the average of the 2 sets of data did not drastically increase the overall prediction.