Table 3.

Magnitude of facilitated firing rate modulations

Region Manipulated	Region Recorded	Condition	Magnitude, spikes/trial	MWU	P Value
M1	Layers II/III	Control	2.66 ± 0.14
		Saline	2.51 ± 0.17	5807	0.0841	n.s.
		Muscimol	2.03 ± 0.17
	Layer IV	Control	1.91 ± 0.09
		Saline	2.21 ± 0.22	2632	0.3673	n.s.
		Muscimol	2.24 ± 0.19
	Layers V/VI	Control	2.40 ± 0.14
		Saline	2.32 ± 0.18	5103	0.0113	*
		Muscimol	3.18 ± 0.31
S1	Layers II/III	Saline	1.70 ± 0.13	889	0.6492	n.s.
		Muscimol	1.72 ± 0.12
	Layer IV	Saline	2.14 ± 0.16	2259	0.8758	n.s.
		Muscimol	2.07 ± 0.19
	Layers V/VI	Saline	3.14 ± 0.21	13640	0.0036	†
		Muscimol	2.41 ± 0.15

Values are means ± SE. Inactivation of ipsilateral M1 or S1 contralateral to the recording site selectively modulated infragranular layers of S1. After M1 inactivation, an increase in the magnitude of facilitated firing rate modulations was observed, and a nonsignificant trend was observed in neurons recorded from the supragranular layers. After contralateral S1 inactivation, a reduction in the magnitude of facilitated firing rate modulations was observed in neurons recorded from the infragranular layers of S1.

^*P < 0.05,

^†P < 0.01.

MWU, Mann-Whitney U-test.