Table 2.

Effect of drug treatment on gene expression in YB5 cells

Methylation	Expression	Quadrant	Analyzed genes	Regulated genes	Change	DAC	Carbo	DAC + Carbo	P value*
<10 %	≥7.08	Q1	5697	1514	Up	177	755	527	<0.0001
					Down	58	365	312	<0.0001
≥10 %	≥7.08	Q2	1119	334	Up	64	150	149	<0.0001
					Down	14	81	61	<0.0001
<10 %	<7.08	Q3	479	22	Up	4	15	7	0.0224
					Down	0	0	0	n/a
≥10 %	<7.08	Q4	1788	73	Up	21	29	44	0.0119
					Down	1	0	0	n/a

^*Chi-square test