Figure 1. Incidence of secondary skin lesions by dose cohort of XL888.
Chart shows the incidence of hyperproliferative/neoplastic skin lesions (melanoma, SCC: squamous cell carcinoma, KA: keratoacanthoma, and VV: verucca vulgaris, stratified by XL888 dose cohort (cohort 1: 30mg; cohort 2: 45mg; cohort 3: 90mg; cohort 4: 135mg). Data shows number of lesions of each type for each individual patient. Cohort had 7 total events (3/3 patients), cohort 2 had 6 total events (2/3 patients), cohort 3 had 3 total events (2/3 patients) and cohort 4 had 3 total events (2/6 patients).