. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: J Invest Dermatol. 2015 Jun 1;135(10):2394–2401. doi: 10.1038/jid.2015.197

Table 3.

Association between MC1R SNPs and risk of severe HTS.

	All subjects (N = 413)			White subjects (N = 327)

MC1R SNP	PR_adj¹	95% CI	P	PR_adj²	95% CI	P
V60L	1.00	0.76-1.31	0.995	1.04	0.79-1.38	0.778
V92M	1.08	0.75-1.55	0.681	0.78	0.47-1.30	0.340
R151C	1.29	1.01-1.64	0.042	1.25	0.95-1.66	0.115
R163Q	1.35	1.14-1.53	<0.001	1.46	1.20-1.78	<0.001
T314T	1.12	0.84-1.50	0.440	1.45	0.94-2.24	0.095

Adjusted prevalence-ratio associated with each additional copy of the rare allele, estimated using data from all study subjects, and adjusted for age, sex, burn size, number of operations, and race.

Adjusted prevalence-ratio associated with each additional copy of the rare allele, estimated using data from White subjects only, and adjusted for age, sex, burn size, and number of operations.

Bold indicates statistical significance after accounting for multiple testing in each model (P<0.01).