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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J Invest Dermatol. 2015 Jun 1;135(10):2394–2401. doi: 10.1038/jid.2015.197

Table 5.

Association between MC1R SNPs and severity of post-burn pruritus.

All subjects (N = 412) White subjects (N = 326)
MC1R SNP β1 95% CI P β2 95% CI P
V60L −0.18 −0.82-0.46 0.583 −0.13 −0.81-0.56 0.718
V92M 0.28 −0.91-1.48 0.645 0.22 −1.67-2.10 0.822
R151C 0.09 −0.65-0.83 0.810 0.26 −0.52-1.04 0.515
R163Q 0.55 −0.07-1.18 0.084 0.57 −0.17-1.32 0.130
T314T −1.18 −2.23-−0.12 0.029 −1.36 −3.13-0.41 0.131
1

Linear regression coefficient estimated using data from all study subjects, representing the difference in mean itch score associated with each additional copy of the rare allele, and adjusted for age, sex, burn size, number of operations, race, and HTS severity.

2

Linear regression coefficient estimated using data from White subjects, representing the difference in mean itch score associated with each additional copy of the rare allele, and adjusted for age, sex, burn size, number of operations, and HTS severity.