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. Author manuscript; available in PMC: 2016 Sep 11.
Published in final edited form as: Circ Res. 2015 Aug 13;117(7):634–644. doi: 10.1161/CIRCRESAHA.115.306850

Figure 1. Characterization of Porcine Allogeneic MSCs and CDCs.

Figure 1

Summary of MSC and CDC characterization by flow cytometry and immunohistochemistry (n=9 each cell type; corresponding with cell donor and passage at the time of each cell injection). The antigenic profile was similar between cell types, as MSCs and CDCs were each predominately CD90+, CD105+ and CD45−, with a small number of cKit+ cells (lower left figure). In contrast, CDCs exhibited uniform expression of the cardiac transcription factors GATA4 and Nkx2.5, demonstrating their commitment to a cardiac lineage, while MSCs did not express GATA4 or Nkx2.5 (top image and lower right figure).