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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Arch Oral Biol. 2015 Jul 14;60(10):1503–1509. doi: 10.1016/j.archoralbio.2015.07.006

Table 1.

Biomarkers assessed in this study and their biological functions

Biomarkers Functional Relevance (References: 10, 11, 12 and 13)
Alpha-fetoprotein

  • Modulate inflammatory events in human skin.

  • Used to detect developmental abnormalities and cancers
Granzyme B

  • Induces inflammation by stimulating cytokine release

  • Higher serum levels in obese patients
IL-1 Receptor Antagonist

  • Inhibits pro-inflammatory effect of IL-1α/IL-1β

  • Higher levels in metabolic syndrome (obesity is a component)
sCD40L

  • Regulates immune/inflammatory functions

  • Implicated in the pathophysiology of severe chronic inflammatory diseases

  • Higher serum levels in obese patients