Table 1. Coronary Artery Calcification in Type 1 Diabetes Study (CACTI) Participants with Type 1 DM at Baseline.
| Men (n=298) | Women (n=354) | p-value | |
|---|---|---|---|
|
| |||
| Age (years) | 37 ± 9 | 36 ± 9 | 0.07 |
|
| |||
| Diabetes duration (years) | 24 ± 9 | 23 ± 9 | 0.29 |
|
| |||
| Hemoglobin A1c [HbA1c] (%) | 8.0 ± 1.2 | 8.0 ± 1.3 | 0.90 |
|
| |||
| Low-density lipoprotein-cholesterol [LDL-C] (mg/dL) | 104 ± 30 | 98 ± 28 | 0.007 |
|
| |||
| High-density lipoprotein-cholesterol [HDL-C] (mg/dL) | 51 ± 14 | 60 ± 17 | <0.0001 |
|
| |||
| Estimated insulin sensitivity [eIS] (mg * kg -1 * min -1) | 3.8 ± 1.4 | 4.8 ± 1.6 | <0.0001 |
|
| |||
| Body mass index [BMI] (kg/m2) | 26.5 ± 3.9 | 26.0 ± 4.7 | 0.09 |
|
| |||
| Triglycerides [TG] (mg/dL) | 80 (61-113) | 77 (61-104) | 0.23 |
|
| |||
| Non-high-density lipoprotein-cholesterol [nonHDL-C] at baseline (mg/dL) | 123 ± 33 | 116 ± 32 | 0.007 |
|
| |||
| Non-high-density lipoprotein-cholesterol [nonHDL-C] at 3-years (mg/dL) | 117 ± 30 | 114 ± 31 | 0.33 |
|
| |||
| Apolipoprotein B at baseline [apoB] (mg/dL) | 94 ± 25 | 89 ± 23 | 0.003 |
|
| |||
| Apolipoprotein B at 3-years [apoB] (mg/dL) | 87 ± 20 | 85 ± 22 | 0.30 |
|
| |||
| Non-high-density lipoprotein-cholesterol [nonHDL-C] ≥130mg/dL | 38% | 27% | 0.004 |
|
| |||
| Apolipoprotein B [apoB] ≥90mg/dL | 50% | 48% | 0.53 |
|
| |||
| On antihypertensive medications | 41% | 35% | 0.09 |
|
| |||
| On statins | 21% | 13% | 0.004 |
|
| |||
| Ever smoker (% yes) | 18% | 22% | 0.21 |
|
| |||
| Any coronary artery calcification [CAC] at baseline | 49% | 28% | <0.0001 |
|
| |||
| Coronary artery calcification progression [CACp] over 6-years | 53% | 34% | <0.0001 |
Data are means ± standard deviation, % or median (25th – 75th %)