Table 2. Multivariable Logistic Regression Models with Coronary Artery Calcification Progression in Adults with Type 1 DM.

Baseline apoB (elevated ≥ 90 mg/dL or normal <90 mg/dL) Baseline nonHDL-C (elevated ≥ 130 mg/dL or normal <130 mg/dL)
CAC progression over 6-years	OR, 95% CI*	OR, 95% CI*	OR, 95% CI*
Elevated apoB and elevated nonHDL-C (n=196)	190 (1.15-3.15) p=0.01	2.86 (1.43-5.74) p=0.003	1.11 (0.15-8.45) p=0.92
Normal apoB and elevated nonHDL-C (n=10)	1.71 (0.23-12.82) p=0.60	2.57 (0.33-20.28) p=0.37	1.00 (reference)
Elevated apoB and normal nonHDL-C (n= 116)	0.67 (0.35-1.26) p=0.21	1.00 (reference)	0.39 (0.05-3.07) p=0.37
Normal apoB and normal nonHDL-C (n=330)	1.00 (reference)	1.50 (0.79-2.85) p=0.21	0.59 (0.08-4.38) p=0.60
Baseline apoB (at or above means ≥ 91.4 mg/dL or below means < 91.4 mg/dL) Baseline nonHDL-C (at or above means ≥ 119.0 mg/dL or below means <119.0 mg/dL)
CAC progression over 6-years	OR, 95% CI*	OR, 95% CI*	OR, 95% CI*
Above means for apoB and nonHDL-C (n=247)	1.67 (1.04-2.67) p=0.03	5.24 (1.58-17.43) p=0.007	1.57 (0.62-3.97) p=0.34
Above means for nonHDL-C only (n=41)	1.06 (0.04-2.67) p=0.90	3.34 (0.79-14.07) p=0.10	1.00 (reference)
Above means for apoB only (n=39)	0.32 (0.10-1.05) p=0.06	1.00 (reference)	0.30 (0.07-1.26) p=0.10
ApoB and nonHDL-C at or below mean (n=325)	1.00 (reference)	3.14 (0.95-10.33) p=0.06	0.94 (0.38-2.36) p=0.90

Each column represents the same logistic regression model, but with a different reference group.

^*The logistic regression models are adjusted for sex, age, duration, HbA1c and statin use.

The first column reports the associations with CAC progression among the apoB and nonHDL-C groups with normal apoB and normal nonHDL-C as the reference group. The middle column represents the same model but with elevated apoB and normal HDL-C as the reference group. The last column represents the same model but with normal apoB and elevated nonHDL-C as a reference group.