Skip to main content
. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J Invest Dermatol. 2015 Jun 1;135(10):2410–2417. doi: 10.1038/jid.2015.195

Figure 3.

Figure 3

IFN-β induces both IL-27 and IL-10. Total mRNA was isolated from L-lep (n=6), T-lep (n=10) and RR (n=7) skin lesions, and the (a) IL-27p28 and (b) IL-27 EBI3 mRNA levels were analyzed by microarray. (c) Correlation of IL-27p28 and IL-10 detected by microarray (arbitrary units (AU)). (d) No correlation was seen between IL-27 EBI3 and IL-10 by microarray (AU). (e) Total mRNA was isolated from L-lep (n=10), Tlep (n=10) and RR (n=10) skin lesions, IL-27p28 and IL-10 mRNA levels were analyzed by TaqMan qPCR. The levels of IL-27p28 were normalized to GAPDH levels in the same tissue. (f) Correlation between IL- 27p28 and IL-10 measured by qPCR. Statistical significance was calculated by One way ANOVA with Kruskal-Wallis post hoc analysis; **, p ≤ 0.01; *, p ≤ 0.05