Table 2.
Left ventricular characteristics on cardiac magnetic resonance (CMR) imaging by study group
Variable | Total (n=83) | Type of Cardiomyopathy | p-value† | |
---|---|---|---|---|
Ischemic* (n=36) | Non-ischemic* (n=47) | |||
Ejection fraction (%) | 27.1 ± 8.1 | 26.7 ± 6.9 | 27.4 ± 8.9 | 0.71 |
End-diastolic volume (mL) | 240.0 ± 80.3 | 226.2 ± 62.3 | 250.3 ± 91.0 | 0.18 |
End-systolic volume (mL) | 178.2 ± 74.2 | 167.9 ± 57.7 | 186.2 ± 84.4 | 0.27 |
Late gadolinium enhancement‡ | ||||
Absent | 19 (23%) | 3 (8%) | 16 (34%) | 0.01 |
Non-ischemic only pattern | 17 (20%) | 1 (3%) | 16 (34%) | <0.001 |
Ischemic only pattern | 38 (46%) | 27 (75%) | 11 (23%) | <0.001 |
Ischemic and non-ischemic patterns | 9 (11%) | 5 (14%) | 4 (9%) | 0.50 |
Cine (regional wall motion abnormality) | 30 (36%) | 20 (56%) | 10 (21%) | 0.003 |
FPP (presence of hypoperfusion) (n=68) | 34 (50%) | 20 (69%) | 14 (36%) | 0.01 |
Clinical algorithm§ | 47 (57%) | 31 (86%) | 16 (34%) | <0.001 |
Diagnosed using Felker’s criteria on coronary angiography
Ischemic versus non-ischemic cardiomyopathy cohort comparison
Non-ischemic pattern is defined as midwall and/or subepicardial late gadolinium enhancement, and ischemic pattern is defined as subendocardial and/or transmural late gadolinium enhancement
Patients categorized as mixed cardiomyopathy by the clinical algorithm (see Figure 1) are categorized as ischemic cardiomyopathy by CMR
Continuous variables are presented as mean ± standard deviation and compared using independent sample t-test. Categorical variables are presented as n (proportion) and compared using the Fisher’s exact test.